The Science Behind NextDay Cheers

1. Power Duo: DHM + L-cysteine

What they do

  • Dihydromyricetin (DHM)*1, 2, 3, 4*

    • Locks onto the same calming brain receptors alcohol uses, so your nerves don’t rebound into jitters once the buzz is gone.
    • Gives liver enzymes a gentle push, helping them finish off leftover alcohol and acetaldehyde (the toxin behind “morning-after” misery).
    • Small human trial: 300 mg DHM cut next-day headache and fatigue by almost 50%, we offer 1,200 mg of DHM per dose.
  • L-cysteine *5, 6, 7*

    • The sulfur in cysteine grabs acetaldehyde and turns it into a harmless compound you can flush out.
    • Rebuilds glutathione, the liver’s lead antioxidant, so cells cope better with the chemical stress of acetaldehyde.
    • Finnish crossover study: 600–1200 mg taken during a night out reduced next-day nausea, headache, and stress while blood-alcohol levels stayed the same.

Why it matters
DHM calms the brain; cysteine cleans up the chemical mess. Together they target two main drivers of hangovers—neuro-overload and toxin buildup.


2. The Support Crew

Nutrients that back up the duo

  Role Ingredient Plain-language benefit
Metabolism spark plugs B1, B6, B12 *10, 12* Help the body’s “cleanup” enzymes keep alcohol moving out.
Antioxidant shield Vitamin C, Vitamin E, Milk-thistle silymarin *9, 10, 12* Protect liver cells from free-radical damage that shows up after the party.
Inflammation soother Prickly pear fruit *8* In a Johns Hopkins study it lowered next-day dry mouth and nausea linked to inflammation.
Stomach settler Ginger root extract *11* Long-time nausea remedy; eases queasy feelings in the gut.
Electrolyte re-balancers Sodium, Potassium *12, 13, 14* Replace salts lost on bathroom trips so muscles and nerves keep firing smoothly.


3. How to Use Cheers

  1. Timing – Take the recommended dose while you drink or right after your last round.
  2. Hydrate – A full glass of water with each capsule helps the ingredients dissolve and keeps you from drying out.
  3. Consistency – Cheers works best when taken every time you expect a late night; benefits stack up.

4. What to Expect Tomorrow

  • Fewer headaches and less brain fog
  • Calmer stomach and less nausea
  • More balanced mood instead of jittery “hangxiety”

No product can erase every effect of heavy drinking, but Cheers gives your body the key tools it needs to wake up feeling human again.

 

Sources:

  1. Human Hovenia extract decreases hangover symptoms — https://pubmed.ncbi.nlm.nih.gov/39766963/ 
  2. DHM improves alcohol-related lipid problems in mice — https://pubmed.ncbi.nlm.nih.gov/37680900/ 
  3. Hovenia fruit extract lowers inflammatory hangover markers — https://pubmed.ncbi.nlm.nih.gov/28750942/ 
  4. DHM counters alcohol intoxication and withdrawal in rats — https://pubmed.ncbi.nlm.nih.gov/22219299/ 
  5. L-cysteine supplement reduces human hangover symptoms — https://pubmed.ncbi.nlm.nih.gov/32808029/ 
  6. Cysteine metabolite shown safe in gut-cell model — https://pubmed.ncbi.nlm.nih.gov/22356486/ 
  7. N-acetyl-cysteine fails to help hangovers in study — https://pubmed.ncbi.nlm.nih.gov/39195687/ 
  8. Prickly-pear extract eases inflammatory hangover symptoms — https://pubmed.ncbi.nlm.nih.gov/15226168/ 
  9. Vitamins C & E offset alcohol toxicity in rat liver — https://pubmed.ncbi.nlm.nih.gov/30087544/ 
  10. Silymarin boosts glutathione in alcoholic-cirrhosis patients — https://pubmed.ncbi.nlm.nih.gov/11841050/ 
  11. Ginger extract improves nausea quality-of-life in chemo — https://pubmed.ncbi.nlm.nih.gov/28805667/ 
  12. Systematic review of pharmacologic hangover remedies — https://pubmed.ncbi.nlm.nih.gov/34972259/ 
  13. Review: supplements for alcoholic liver disease — https://pubmed.ncbi.nlm.nih.gov/27498574/ 
  14. Review: nutrient deficits in alcohol use disorder — https://pubmed.ncbi.nlm.nih.gov/38193343/